Description
Product Characteristics:
Aliases: Centrosome Marker antibody, Ken antibody, Kendrin antibody, KIAA0402 antibody, MOPD2 antibody, PCN antibody, PCNT 2 antibody, PCNT antibody, PCNT B antibody, PCNT_HUMAN antibody, PCNT1 antibody, PCNT2 antibody, PCNTB antibody, PCTN2 antibody, Pericentrin 1 antibody, Pericentrin 2 antibody, Pericentrin 380 antibody, Pericentrin antibody, Pericentrin B antibody, Pericentrin-B antibody, SCKL4 antibody
Target Information: The protein encoded by this gene binds to calmodulin and is expressed in the centrosome. It is an integral component of the pericentriolar material (PCM). The protein contains a series of coiled-coil domains and a highly conserved PCM targeting motif called the PACT domain near its C-terminus. The protein interacts with the microtubule nucleation component gamma-tubulin and is likely important to normal functioning of the centrosomes, cytoskeleton, and cell-cycle progression. Mutations in this gene cause Seckel syndrome-4 and microcephalic osteodysplastic primordial dwarfism type II. [provided by RefSeq, Jul 2008]